6533b831fe1ef96bd12983d7

RESEARCH PRODUCT

Total synthesis of (−)-mintlactone

Miguel CardaJ. Alberto Marco

subject

chemistry.chemical_classificationBicyclic moleculechemistryStereochemistryOrganic ChemistryDrug DiscoveryTotal synthesisMINTLACTONEStereoselectivityEnantiomerRing (chemistry)BiochemistryLactone

description

Abstract The first total, stereodirected synthesis of (—)-mintlactone is described. A stereoselective, radical-mediated ring closure was the key step in the synthesis.

https://doi.org/10.1016/s0040-4039(00)93463-4