6533b831fe1ef96bd1298d1b
RESEARCH PRODUCT
Die retraktile Mesenteritis*: Diagnostische und therapeutische Aspekte
C. TrautweinP. KloseElisabeth HermannA. RambowH. GabbertThomas PorallaHanns F. Löhrsubject
medicine.medical_specialtyMesenteric PanniculitisAbdominal painCyclophosphamidebusiness.industryRetractile MesenteritisGeneral MedicineAortic bifurcationSmall intestineSurgerymedicine.anatomical_structurePrednisonemedicinemedicine.symptomPancreasbusinessmedicine.drugdescription
An 18-year-old boy, who had severe abdominal pain for 18 months associated with marked weight loss, was found to have a stenosed ileal sling on double-contrast radiology of the small intestine. At operation a plate-like tumour was extending from the pancreas to the aortic bifurcation. Histological examination of removed tissue revealed retractile mesenteritis (mesenteric panniculitis; liposclerotic mesenteritis). The symptoms regressed and the patient again gained weight under immunotherapy with 1 mg/kg of prednisone and 2 mg/kg of cyclophosphamide daily. Subsequently, under prednisone alone, there was a recurrence, which responded within five weeks to daily 60 mg prednisone and 125 mg cyclophosphamide. The patient remains symptom-free on 125 mg cyclophosphamide and 10 mg prednisone daily.
year | journal | country | edition | language |
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2008-03-25 | DMW - Deutsche Medizinische Wochenschrift |