6533b831fe1ef96bd1299792

RESEARCH PRODUCT

ChemInform Abstract: Modular Hemisyntheses of Boronato- and Trifluoroborato-Substituted L-NHBoc Amino Acid and Peptide Derivatives.

Marie-joëlle EyminHassib AudiEmmanuelle RémondArnaud TessierRaluca Malacea-kabbaraSylvain Jugé

subject

inorganic chemicalschemistry.chemical_classificationChemistryWittig reactionOrganic chemistryPeptideGeneral MedicineAmino acid

description

Modular hemisyntheses of boronato- and trifluoroborato-substituted amino acid derivatives are achieved based on the reaction of Wittig reagent (I) with aldehydes followed by Ir-catalyzed boronation.

https://doi.org/10.1002/chin.201423195