6533b832fe1ef96bd129a580

RESEARCH PRODUCT

Nasal budesonide efficacy for nasal nitric oxide and nasal obstruction in rhinitis

Massimo LandiGiuliana FerranteGiuliana FerranteGiovanni PassalacquaLaura MontalbanoLaura MontalbanoSalvatore FasolaGiovanna CilluffoVelia MaliziaStefania La GruttaStefania La Grutta

subject

MaleBudesonideRhinitis Allergic PerennialImmunologyAdministration Intranasal; Budesonide; Child; Double-Blind Method; Eosinophils; Female; Glucocorticoids; Humans; Male; Nasal Obstruction; Nitric Oxide; Rhinitis Allergic Perennial; Sleep; Pediatrics Perinatology and Child Health; Immunology and Allergy; ImmunologyNitric OxidePediatricsNitric oxidelaw.invention03 medical and health scienceschemistry.chemical_compoundAllergic0302 clinical medicineDouble-Blind MethodRandomized controlled triallawHumansImmunology and AllergyMedicineChild030223 otorhinolaryngologyBudesonideGlucocorticoidsChildrenAdministration IntranasalRhinitisbusiness.industryPerinatology and Child HealthNitric oxide metabolismPerennialNasal obstructionNasal nitric oxideEosinophilsIntranasal030228 respiratory systemchemistryAnesthesiaAdministrationPediatrics Perinatology and Child HealthFemaleNasal administrationSleepbusinessmedicine.drug

description

Nasal nitric oxide (nNO) is a noninvasive tool that may be helpful in evaluating the inflammatory status in the upper airways [1]. Previous studies report that nNO is elevated in children with Allergic Rhinitis (AR) [2], especially in perennial sensitized subjects [3], and that it may be affected by topical administration of intranasal steroids (INSs) [4]. This article is protected by copyright. All rights reserved.

10.1111/pai.12707http://hdl.handle.net/11562/1050481