6533b832fe1ef96bd129af35

RESEARCH PRODUCT

Repetitive TMS temporarily alters brain diffusion

T. DuningAndreas RogalewskiO. SteinstraeterH. KugelA. JansenC. BreitensteinS. KnechtF. M. MottaghyA. Pascual-leoneG. Schlaug

subject

Motor thresholdAdultMaleTime Factorsmedicine.medical_treatmentMotor Cortexdiffusion-weighted imaging repetitive transcranial magnetic stimulationMagnetic Resonance ImagingTranscranial magnetic stimulationDiffusionMagneticsmedicineHumansNeurology (clinical)Primary motor cortexDiffusion (business)PsychologyNeuroscience

description

The authors investigated whether repetitive transcranial magnetic stimulation (rTMS) at 1 Hz (12 minutes; 90% of motor threshold) to the primary motor cortex (M1) leads to changes in diffusion-weighted imaging (DWI). After the rTMS train, there was a temporary small restriction in diffusion within the targeted left M1 that disappeared after 5 minutes. These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects.

yearjournalcountryeditionlanguage
2004-06-07
10.1212/01.wnl.0000058903.15205.46http://hdl.handle.net/10447/436981