6533b833fe1ef96bd129b883
RESEARCH PRODUCT
Marine Indole Alkaloids.
Natalie NetzTill Opatzsubject
540 Chemistry and allied sciencesAquatic Organismscarbolinesprenylated indolesmarine natural productsAntineoplastic AgentsReviewindolesalkaloidsbisindolesdiketopiperazinesIndole AlkaloidsBiological Factorslcsh:Biology (General)Anti-Infective Agents540 ChemieHumansnitrogen heterocycleslcsh:QH301-705.5description
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed.
year | journal | country | edition | language |
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2015-06-30 | Marine drugs |