6533b833fe1ef96bd129b8dc

RESEARCH PRODUCT

The Shwartzman reaction repealed

Sireci GRosenberg H F

subject

Marine sponges1 o (alpha galactopyranosyl) 2 hexacosanoylamino 134 octadecanetriol alpha galactosylceramide lipopolysaccharideImmunologyCell BiologyTh2 cytokinesBiologyNatural killer T cellMicrobiologyEndotoxin shockGlycolipidShock (circulatory)medicineImmunology and Allergylipids (amino acids peptides and proteins)medicine.symptom

description

The article, “ -Galactosylceramide induces protection against lipopolysaccharide-induced shock” (doi:10.1189/jlb.0506298), was selected as a Pivotal Advance because the results suggest that -galactosylceramide ( GalCer), a glycolipid isolated from marine sponges, can protect against the complete morbidity and mortality characterisitic of endotoxin shock by inducing NKT cells to produce TH2 cytokines.

yearjournalcountryeditionlanguage
2007-01-02
10.1189/jlb.1306298http://hdl.handle.net/10447/25720