6533b833fe1ef96bd129c0a0
RESEARCH PRODUCT
ChemInform Abstract: Synthesis of Methyl Derivatives of Linear and Angular Thienocoumarins and Thiopyranocoumarins.
Paolo RodighieroAdriana ChilinGiovanni PastoriniA. Marottosubject
chemistry.chemical_compoundComputational chemistryChemistryPropargyl chlorideOrganic chemistryGeneral Medicinedescription
New linear and angular thienocoumarins and thiopyranocoumarins were synthesized. The key intermediates were appropriate methyl derivatives of 7-mercaptocoumarin, which were condensed with chloro-ketones or propargyl chloride. Thioethers were cyclized under various conditions in order to determine which methods produced the best yields of the desired thienocoumarins 15, 16, 17, 18, 22, 23, 24, 27 and thiopyranocoumarins 28 and 29.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-06-18 | ChemInform |