Prevalence and features of delirium in older patients admitted to rehabilitation facilities

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RESEARCH PRODUCT

Prevalence and features of delirium in older patients admitted to rehabilitation facilities

Chiara Sidoli Antonella Zambon Elena Tassistro Emanuela Rossi Enrico Mossello Marco Inzitari Antonio Cherubini Alessandra Marengoni Alessandro Morandi Giuseppe Bellelli A Tarasconi M Sella G Paternò G Faggian C Lucarelli N De Grazia C Alberto L Porcella I Nardiello E Chimenti M Zeni E Romairone C Minaglia C Ceccotti G Guerra G Mantovani F Monacelli C Minaglia T Candiani F Santolini C Minaglia M Rosso V Bono S Sibilla P Dal Santo M Ceci P Barone T Schirinzi A Formenti G Nastasi G Isaia D Gonella A Battuello S Casson D Calvani F Boni A Ciaccio R Rosa G Sanna S Manfredini L Cortese M Rizzo R Prestano A Greco M Lauriola G Gelosa V Piras M Arena D Cosenza A Bellomo M Lamontagna L Gabbani L Lambertucci S Perego G Parati G Basile V Gallina G Pilone C Giudice L Pietrogrande M Mosca I Corazzin P Rossi V Nunziata F D’amico A Grippa S Giardini R Barucci A Cossu L Fiorin M Arena M Distefano M Lunardelli M Brunori I Ruffini E Abraham A Varutti E Fabbro A Catalano G Martino D Leotta A Marchet G Dell’aquila A Scrimieri M Davoli M Casella A Cartei G Polidori G Basile D Brischetto S Motta R Saponara P Perrone G Russo D Del C Car T Pirina S Franzoni A Cotroneo F Ghiggia G Volpi C Menichetti M Bo A Panico P Calogero G Corvalli M Mauri E Lupia R Manfredini F Fabbian A March M Pedrotti M Veronesi E Strocchi C Borghi A Bianchetti A Crucitti V Difrancesco G Fontana A Geriatria L Bonanni F Barbone C Serrati G Ballardini M Simoncelli G Ceschia C Scarpa R Brugiolo S Fusco T Ciarambino C Biagini E Tonon M Porta D Venuti M Delsette M Poeta G Barbagallo G Trovato A Delitala P Arosio F Reggiani G Zuliani B Ortolani E Mussio A Girardi A Coin G Ruotolo A Castagna M Masina R Cimino A Pinciaroli G Tripodi F Cassadonte M Vatrano L Scaglione P Fogliacco C Muzzuilini F Romano A Padovani L Rozzini A Cagnin F Fragiacomo G Desideri E Liberatore A Bruni G Orsitto M Franco L Bonfrate M Bonetto N Pizio G Magnani G Cecchetti A Longo V Bubba L Marinan M Cotelli M Turla M Brunori M Sessa L Abruzzi G Castoldi D Lovetere C Musacchio M Novello A Cavarape A Bini A Leonardi F Seneci W Grimaldi F Seneci F Fimognari V Bambar A Saitta F Corica M Braga Null Servi E Ettorre C G Camellini Bellelli G Annoni A Marengoni A Bruni A Crescenzo G Noro R Turco M Ponzetto L Giuseppe B Mazzei G Maiuri D Costaggiu R Damato E Fabbro M Formilan G Patrizia L Santuar M Gallucci C Minaglia M Paragona P Bini D Modica C Abati M Clerici I Barbera F Nigroimperiale A Manni C Votino C Castiglioni M Di M Degl’innocenti G Moscatelli S Guerini C Casini D Dini S Denotariis F Bonometti C Paolillo A Riccardi A Tiozzo A Samysalamafahmy A Riccardi C Paolillo M Dibari S Vanni A Scarpa D Zara P Ranieri M Alessandro P Calogero G Corvalli F Di D Pezzoni C Platto V D’ambrosio C Ivaldi P Milia F Desalvo C Solaro M Strazzacappa M Bo A Panico M Cazzadori M Bonetto M Grasso E Troisi G Magnani G Cecchetti V Guerini B Bernardini C Corsini S Boffelli A Filippi K Delpin B Faraci E Bertoletti M Vannucci P Crippa A Malighetti C Caltagirone S Disant D Bettini F Maltese M Formilan G Abruzzese C Minaglia D Cosimo M Azzini M Cazzadori M Colombo G Procino S Fascendini F Barocco P Del F D’amico A Grippa A Mazzone M Cottino G Vezzadini S Avanzi C Brambilla S Orini F Sgrilli A Mello L E Lombardi Muti B Dijk S Fenu C Pes P Gareri A Castagna M Passamonte R Rigo L Locusta L Caser G Rosso S Cesarini R Cozzi C Santini P Carbone I Cazzaniga R Lovati A Cantoni P Ranzani D Barra G Pompilio S Dimori S Cernesi C Riccò F Piazzolla E Capittini C Rota F Gottardi L Merla A Barelli A Millul G De G Morrone M Bigolari C Minaglia M Macchi F Zambon F D’amico F D’amico C Pizzorni G Dicasaleto G Menculini M Marcacci G Catanese D Sprini T Dicasalet M Bocci S Borga P Caironi C Cat E Cingolani L Avalli G Greco G Citerio L Gandini G Cornara R Lerda L Brazzi F Simeone M Caciorgna D Alampi S Francesconi E Beck B Antonini K Vettoretto M Meggiolaro E Garofalo A Bruni S Notaro R Varutti F Bassi G Mistraletti A Marino R Rona E Rondelli I Riva A Cortegiani L Pistidda R D’andrea L Querci P Gnesin M Todeschini M Lugano G Castelli M Ortolani A Cotoia S Maggiore L Ditizio R Graziani I Testa E Ferretti C Castioni F Lombardi R Caserta M Pasqua S Simoncini F Baccarini M Rispoli F Grossi L Cancelliere M Carnelli F Puccini G Biancofiore A Siniscalchi C Laici E Mossello M Torrini G Pasetti S Palmese R Oggioni V Mangani S Pini M Martelli E Rigo F Zuccalà A Cherri R Spina I Calamai N Petrucci A Caicedo F Ferri P Gritti N Brienza R Fonnesu M Dessena G Fullin D Saggioro

subject

Aging Disability Rehabilitation Delirium Delirium; Dementia; Disability; Physical restraint; Rehabilitation Cross-Sectional Studies Activities of Daily Living mental disorders Prevalence Humans Dementia Physical restraint Geriatrics and Gerontology Aged

description

Background: Delirium is thought to be common across various settings of care; however, still little research has been conducted in rehabilitation. Aim: We investigated the prevalence of delirium, its features and motor subtypes in older patients admitted to rehabilitation facilities during the three editions of the “Delirium Day project”. Methods: We conducted a cross-sectional study in which 1237 older patients (age ≥ 65 years old) admitted to 50 Italian rehabilitation wards during the three editions of the “Delirium Day project” (2015 to 2017) were included. Delirium was evaluated through the 4AT and its motor subtype with the Delirium Motor Subtype Scale. Results: Delirium was detected in 226 patients (18%), and the most recurrent motor subtype was mixed (37%), followed by hypoactive (26%), hyperactive (21%) and non-motor one (16%). In a multivariate Poisson regression model with robust variance, factors associated with delirium were: disability in basic (PR 1.48, 95%CI: 1.17–1.9, p value 0.001) and instrumental activities of daily living (PR 1.58, 95%CI: 1.08–2.32, p value 0.018), dementia (PR 2.10, 95%CI: 1.62–2.73, p value < 0.0001), typical antipsychotics (PR 1.47, 95%CI: 1.10–1.95, p value 0.008), antidepressants other than selective serotonin reuptake inhibitors (PR 1.3, 95%CI: 1.02–1.66, p value 0.035), and physical restraints (PR 2.37, 95%CI: 1.68–3.36, p value < 0.0001). Conclusion: This multicenter study reports that 2 out 10 patients admitted to rehabilitations had delirium on the index day. Mixed delirium was the most prevalent subtype. Delirium was associated with unmodifiable (dementia, disability) and modifiable (physical restraints, medications) factors. Identification of these factors should prompt specific interventions aimed to prevent or mitigate delirium.

year	journal	country	edition	language
2022-08-01	Aging Clinical and Experimental Research

10.1007/s40520-022-02099-8 https://doi.org/10.1007/s40520-022-02099-8