6533b833fe1ef96bd129c460
RESEARCH PRODUCT
Dimethyl 2-(1-methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)malonate
Antonia Di MolaRosanna FilosaAntonio Massasubject
isobenzofuranoneTandem010405 organic chemistryOrganic Chemistrycascade reactions010402 general chemistry01 natural sciencesBiochemistryDimethyl malonateMedicinal chemistryquaternary carbonlcsh:QD146-1970104 chemical sciencesPhthalidechemistry.chemical_compoundMalonatechemistrylcsh:Inorganic chemistryphthalidePhysical and Theoretical ChemistryQuaternary carbondescription
In this work we report a facile access to a 3,3-disubstituted isobenzofuranone by tandem addition/cyclization reaction to methyl 2-acetylbenzoate in the presence of dimethyl malonate, under basic conditions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-04-01 |