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RESEARCH PRODUCT
Metabolism and Lysine Biosynthesis Control in Brevibacterium Flavum: Impact of Stringent Response in Bacterial Cells
M. RuklishaR. JoninaG. PetrovicaL. Paeglesubject
Stringent responseLysineGuanosineMetabolismBiologycomplex mixturesCorynebacterium glutamicumchemistry.chemical_compoundchemistryBiochemistryBrevibacterium flavumbacteriaThreonineIntracellulardescription
Parameters affecting lysine biosynthesis by Brevibacterium flavum RC 115 cells under stringent response conditions (test guanosine 5′-diphosphate 3′-diphosphate accumulation in cells) caused by threonine limitation were investigated. Experimental results confirmed that an increase in lysine biosynthesis by this bacterium under stringent response conditions might be a result of an increase in the intracellular concentration of NADPH as well as lysine export activity.
year | journal | country | edition | language |
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2005-12-11 |