6533b834fe1ef96bd129d4ea

RESEARCH PRODUCT

Rapid hydrolysis of benzodiazepines to benzophenones in a microwave oven

Manuel GómezAmparo SalvadorZ.a. De BenzoM. De La Guardia

subject

ChemistryMicrowave ovenBiochemistryAnalytical Chemistrychemistry.chemical_compoundHydrolysisReaction rate constantBenzophenoneEnvironmental ChemistryOrganic chemistrySpectroscopyMicrowaveNuclear chemistryUv spectrophotometry

description

Abstract A microwave oven is used to carry out the complete hydrolysis of diazepam to the corresponding benzophenone in only 10 min, at 650 W, with good recovery. The reaction yield is evaluated by first-derivative UV spectrophotometry.

https://doi.org/10.1016/s0003-2670(00)83451-0