6533b834fe1ef96bd129d827

RESEARCH PRODUCT

Caseicin, a bacteriocin from Lactobacillus casei.

E. MüllerF. Radler

subject

DNA BacterialLactobacillus caseibiologyStrain (chemistry)Biological Transport ActiveFructoseGeneral MedicineFructosebiology.organism_classificationMicrobiologyMicrobiologyMolecular Weightchemistry.chemical_compoundLacticaseibacillus caseiPlasmidGlucoseBiochemistrychemistryBacteriocinBiosynthesisBacterial ProteinsBacteriocinsThermolabileBacteria

description

The intracellular bacteriocin caseicin 80 was purified from cell extracts of Lactobacillus casei strain B80. It is a thermolabile protein with an apparent molar mass of 42 kDa. As no plasmids were observed in the bacteriocinogenic strain it is assumed that caseicin is encoded by the bacterial chromosome. Using 14C-labelled precursors it was found that biosynthesis of DNA and proteins was influenced by caseicin but this inhibition is probably not the primary effect. The incorporation of fructose but not of glucose into cellular material was inhibited by caseicin.

10.1007/bf02814392https://pubmed.ncbi.nlm.nih.gov/8150392