How a Second Mg2+ Ion Affects the Phosphoryl-Transfer Mechanism in a Protein Kinase: A Computational Study

6533b834fe1ef96bd129df76

RESEARCH PRODUCT

How a Second Mg2+ Ion Affects the Phosphoryl-Transfer Mechanism in a Protein Kinase: A Computational Study

Iñaki Tuñón Jans Alzate-morales Kirill Zinovjev Rodrigo Recabarren

subject

biology Chemistry Kinase Cyclin-dependent kinase 2 Transfer mechanism Biophysics biology.protein A protein General Chemistry Kinase activity Catalysis Ion

description

Mg2+ ions are essential for the proper functioning of protein kinases, and their roles in kinase activity have been studied for years. However, recent investigations have shed light on how these me...

year	journal	country	edition	language
2020-12-15	ACS Catalysis

https://doi.org/10.1021/acscatal.0c03304

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