6533b834fe1ef96bd129dfb8

RESEARCH PRODUCT

Stereoselektive synthese von D-α-hydroxycarbonsäuren bzw. D-α-hydroxycarbonsäuren enthaltenden depsipeptiden aus L-aminosäuren

Horst KunzHans-georg Lerchen

subject

chemistry.chemical_classificationDepsipeptideChemistryStereochemistryCaesiumOrganic ChemistryDrug Discoverychemistry.chemical_elementBiochemistryAmino acid

description

Abstract Depsipeptides containing D-α-hydroxy carboxylic acids are efficiently synthesized by the reactions of L-α-halo-carboxylic acid esters (obtained from L-amino acids) with caesium salts of N-protected amino acids.

https://doi.org/10.1016/s0040-4039(00)95009-3