Inherited pericentric inversion of human chromosome 5.

6533b834fe1ef96bd129e0d2

RESEARCH PRODUCT

Inherited pericentric inversion of human chromosome 5.

subject

Genetics Heterozygote Chromosome Heterozygote advantage Biology Human genetics Primary Myelofibrosis Chromosome Inversion Genetics Humans Female Chromosomes Human 4-5 Genetics (clinical)Chromosomal inversion Aged

description

Une inversion pericentrique heterozygote du chromosome 5 a ete decouverte dans les cellules de la moelle osseuse et dans les lymphocytes peripheriques stimules par le phytohemagglutinine d'une femme de 75 ans atteinte de myelofibrose et de metaplasie myeloide. L'inversion etait presente dans 100% des metaphases etudiees. Les points de cessure du chromosome 5 etaient localises en k15 et q10. Une etude de la famille est presentee

year	journal	country	edition	language
1983-12-01	Human genetics

10.1007/bf00286670 https://pubmed.ncbi.nlm.nih.gov/6654338

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