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RESEARCH PRODUCT
Effect of in vitro exposure to cadmiumand copper on sea bass blood cells
Aiti VizziniMaria Luigia Di BellaMirella VazzanaVincenzo ArizzaMonica CeliGiuseppina SalernoDaniela Parrinellosubject
Neutral redFish blood cells NR MTT040301 veterinary scienceschemistry.chemical_elementEnvironmental pollution0403 veterinary scienceToxicologychemistry.chemical_compoundMTT assaySea basslcsh:SF1-1100Cadmiumbiology0402 animal and dairy scienceAquatic animal04 agricultural and veterinary sciencesbiology.organism_classification040201 dairy & animal scienceMolecular biologyIn vitrochemistryFish blood cells Heavy metals NR MTTAnimal Science and ZoologyDicentrarchuslcsh:Animal culturedescription
Blood cells freshly collected from sea bass (Dicentrarchus labrax) were exposed in vitro to different concentrations of cadmium (Cd) and copper (Cu) at 10-7 M, 10-5 M, 10-3 M, and exam- ined for neutral red retention capacity and for cell vitality with MTT assay. A relationship between heavy metal exposure and alteration in responses of blood cells in a dose-time-dependent was found. Our results showed that fish blood cells may constitute an interesting biological model for experimen- tal and applied toxicology, especially in the case of environmental pollution.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-01-01 |