6533b835fe1ef96bd129e8ef

RESEARCH PRODUCT

ChemInform Abstract: Oxidative Cyclization of Some Aldehyde Semicarbazones Induced by Metallic Salts.

Renato NotoPaolo Lo MeoGiuseppe WerberFrancesco BuccheriMichelangelo GruttadauriaGiuseppe Cusmano

subject

chemistry.chemical_classificationOxidative cyclizationRegioselectivityGeneral MedicineRing (chemistry)AldehydeMetalchemistryvisual_artYield (chemistry)Polymer chemistryOxidizing agentTriazole derivativesvisual_art.visual_art_mediumOrganic chemistry

description

The oxidative cyclization of some aldehyde semicarbazones 10 with four different oxidizing agents has been effected. The structure of the semicarbazones and the nature of cyclizing agent affected the rate and yield of cyclization but they did not show any influence on the regiochemistry of reaction. In fact, 1,2,4-triazoline 20 was the only heterocyclic ring obtained by the cyclization reaction.

https://doi.org/10.1002/chin.199349180