6533b835fe1ef96bd129ec3b

RESEARCH PRODUCT

A new synthetic entry into the tricyclo[3.3.0.03,7] octane skeleton

Pelayo CampsRoberto LozanoMiguel A. MirandaM.j RodrǐguezC. Iglesias

subject

Diketonechemistry.chemical_compoundBicyclic moleculeChemistryOrganic ChemistryDrug DiscoveryOrganic chemistrySkeleton (category theory)BiochemistryPolyquinaneOctane

description

Abstract A short synthesis of dimethyl tricyclo[3.3.0.03,7] octane-1,5-dicarboxylate, 13 , and its 3,7-dimethyl-derivative, 14 , by iodine oxidation of the bis-enolate derived from the corresponding dimethyl cis -bicyclo[3.3.0] octane-3,7-dicarboxylate, 11 or 12 , is described.

http://www.scopus.com/inward/record.url?eid=2-s2.0-0001583356&partnerID=MN8TOARS