Latvijas rūpniecībai aktuālu farmaceitiski aktīvo vielu kristālsolvāti

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RESEARCH PRODUCT

Latvijas rūpniecībai aktuālu farmaceitiski aktīvo vielu kristālsolvāti

subject

thermodynamical stability Chemistry kristālsolvāti nestehiometriskie solvāti vielu termodinamiskā stabilitāte nonstoichiometric solvates phase transition kinetics Ķīmija ķīmijas tehnoloģijas un biotehnoloģija fāžu pāreju kinētika vielas stāvokļa diagramma crystal solvates Ķīmija phase diagram

description

ANOTĀCIJA Promocijas darbs veltīts Latvijas tautsaimniecībai aktuālu farmaceitiski aktīvo vielu (FAV) izpētei. Veikti apskatīto vielu kristālsolvātu meklējumi un iegūtas līdz šim neaprakstītas vielu kristāliskās formas. Novērtēta iegūto formu stabilitāte iegūšanas, ražošanas un uzglabāšanas apstākļos. Atsevišķām FAV veikta struktūras noteikšana, gan izmantojot pulvera rentgendifraktometriju, gan monokristālu rentgendifraktometriju. Iegūtie rezultāti ir aktuāli zāļu ražotājiem, kā arī tiem ir zinātniska nozīme no FAV īpašību apzināšanas un metožu attīstības viedokļa. Atslēgas vārdi: kristālsolvāti, vielas stāvokļa diagramma, nestehiometriskie solvāti, vielu termodinamiskā stabilitāte, fāžu pāreju kinētika.

year	journal	country	edition	language
2013-01-01

https://dspace.lu.lv/dspace/handle/7/4719

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
  - PE2_2 Phenomenology of fundamental interactions
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  - PE2_10Atomic, molecular physics
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SHSocial Sciences and Humanities
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