6533b835fe1ef96bd129f522

RESEARCH PRODUCT

Nanoreactors for the multi-functionalization of poly-histidine fragments

Claudia BonechiAndrea CappelliFrancesco MakovecEugenio PaccagniniMarco PaolinoMariangela GentileMichela VisintinFrancesco TavantiLaura SalviniAnnalisa RealeVincenzo RazzanoMariano LicciardiMaria Cristina MenzianiAlessandro DonatiGianfranco CaselliCinzia ScialabbaGermano Giuliani

subject

ChemistryShell (structure)Core (manufacturing)General ChemistryNanoreactorCatalysisNanoreactorschemistry.chemical_compoundChemical engineeringMaterials ChemistryWater environmentSurface modificationEthylene glycolHistidine

description

Water-soluble MBHA derivatives were found to self-assemble in a water environment to generate aggregates showing core–shell architectures. The aggregates appeared to be capable of working as nanoreactors performing a multi-functionalization of poly-histidine fragments, which after an initial interaction with the solvated oligo(ethylene glycol) shell reach the reactive core.

10.1039/c9nj00279khttp://hdl.handle.net/10447/368730