6533b835fe1ef96bd12a0100
RESEARCH PRODUCT
Therapeutic plasma exchange: Review of current indications
Miguel Fernández-zarzosoJavier De La RubiaInés Gómez-seguísubject
medicine.medical_specialtyPlasma Exchangebusiness.industryPlasmapheresisHematology030204 cardiovascular system & hematologyExtracorporeal03 medical and health sciences0302 clinical medicineApheresismedicineHumansExtracorporeal techniqueTherapeutic plasma exchangeIntensive care medicinebusiness030215 immunologyWhole blooddescription
Therapeutic plasma exchange (TPE) is the extracorporeal technique performed in an apheresis device were patient's plasma is separated from whole blood and removed, while the cellular blood components are returned to the patient together with a replacement fluid. By the extracorporeal removal of pathological substances and the replacement of deficient plasma components, it constitutes an important tool for the management of several disorders and it is a well-known and established treatment for numerous diseases. Additionally, overall available data confirm the safety and efficacy of TPE. Nevertheless, the quality of the evidence supporting the utility and efficacy of the procedure is diverse. This review attempts to compile the current indications of TPE in different disorders according to an extensive and updated literature review, with special focus on its present role and its validity in the twenty-first century medicine.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-06-01 | Transfusion and Apheresis Science |