6533b835fe1ef96bd12a0167

RESEARCH PRODUCT

An efficient synthesis of new fluorinated uracil derivatives.

Julio PieraEsther SalavertJuan F. Sanz-cerveraAmparo AsensioSantos Fustero

subject

Hydrocarbons FluorinatedSynthesis ; Fluorinated uracil derivatives ; Oxazolines ; Biologically activeAntimetabolitesUNESCO::QUÍMICABiologically active:QUÍMICA::Química orgánica [UNESCO]UracilGeneral MedicineOxazolines:QUÍMICA [UNESCO]Combinatorial chemistryFluorinated uracil derivativesSynthesischemistry.chemical_compoundchemistryNitrilesUNESCO::QUÍMICA::Química orgánicaUracilOxazoles

description

A series of potentially biologically active fluorinated uracil derivatives has been prepared in three steps from oxazolines and fluorinated nitriles with good chemical yields. Fustero Lardies, Santos, Santos.Fustero@uv.es ; Sanz Cervera, Juan Francisco, Juan.F.Sanz@uv.es ; Asensio Martinez, Amparo, Amparo.Asensio@uv.es

https://pubmed.ncbi.nlm.nih.gov/12739640