6533b836fe1ef96bd12a09ae

RESEARCH PRODUCT

Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator

E. D. SitsanidisP. M. KasapidouJ. R. HiscockV. GubalaH. CastelP. I. A. PopoolaA. J. HallA. A. Edwards

subject

geelitsyöpäsolutPhenylalanineOrganic ChemistryQglioblastoomabiologinen aktiivisuusHydrogelsDipeptidesPhysical and Theoretical ChemistryBiochemistryorgaaniset yhdisteet

description

Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells. peerReviewed

yearjournalcountryeditionlanguage
2022-09-13
10.1039/d2ob01339hhttps://kar.kent.ac.uk/96699/19/Sitsanidis_Probing.pdf