6533b836fe1ef96bd12a0b6c
RESEARCH PRODUCT
Investigating the use of primary adult subventricular zone neural precursor cells for neuronal replacement therapies
Daniel G. HerreraNuria FlamesDaniel A. LimLucı́a Colladosubject
NeuronsStem CellsGeneral NeuroscienceGraft SurvivalNeurogenesisCentral nervous systemBrainSubventricular zoneCell DifferentiationNeurodegenerative DiseasesBiologyMammalian brainNeural stem cellBrain repairTransplantationmedicine.anatomical_structureCell MovementLateral VentriclesPrecursor cellmedicineAnimalsHumansBrain Tissue TransplantationNeuroscienceStem Cell Transplantationdescription
With the relatively recent discovery that neurogenesis persists throughout life in restricted regions of the adult mammalian brain, including those of human beings, there has been great interest in the use of adult-derived neural stem cells for neuronal replacement. There are many great hurdles that must be overcome in order for such replacement strategies to succeed. In this review, we outline some of these hurdles and discuss recent experiments that investigate the potential of using neural precursor cells found in the subventricular zone of the adult brain for brain repair.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2002-05-29 | Brain Research Bulletin |