6533b836fe1ef96bd12a0fc8

RESEARCH PRODUCT

The cytotoxic properties of Natural Coumarins Isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives aegelinol

Rosselli SergioMaggio Antonella MariaFaraone NicolettaSpadaro VivienneMorris-natschke Susan LBastow Kenneth FLee Kuo-hsiungBruno Maurizio

subject

Magnetic Resonance SpectroscopyCell SurvivalCoumarinsCell Line TumorHumansApiaceae Ferulago campestris coumarins aegelinol derivatives cytotoxicitySettore CHIM/06 - Chimica OrganicaDrug Screening Assays AntitumorAntineoplastic Agents PhytogenicPlant RootsApiaceae

description

Grandivittin (1), agasyllin (2), aegelinol benzoate (3) and felamidin (20), four natural coumarins isolated from Ferulago campestris, and several synthetic ester derivatives of aegelinol (4) were tested against four tumor cell lines. Some of them were shown to be marginally cytotoxic against the A549 lung cancer cell line.

yearjournalcountryeditionlanguage
2010-02-03
http://hdl.handle.net/10447/46012