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RESEARCH PRODUCT
Bacteriophage imaging : past, present and future
Gabriel Magno De Freitas AlmeidaLotta-riina SundbergIlari MaasiltaMiika Leppänensubject
0301 basic medicineviruksetviruses02 engineering and technologyComputational biologyvirusBiologymikroskopiaMicrobiologyHistory 21st CenturybakteriofagitBacteriophage03 medical and health sciencesbacteriophagephageAnimalsHumansBacteriophagesstructureMolecular BiologyMicroscopyBacteriaVirionGeneral MedicineHistory 20th Century021001 nanoscience & nanotechnologybiology.organism_classificationMolecular Imaging030104 developmental biologykuvantaminen0210 nano-technologydescription
The visualization of viral particles only became possible after the advent of the electron microscope. The first bacteriophage images were published in 1940 and were soon followed by many other publications that helped to elucidate the structure of the particles and their interaction with the bacterial hosts. As sample preparation improved and new technologies were developed, phage imaging became important approach to morphologically classify these viruses and helped to understand its importance in the biosphere. In this review we discuss the main milestones in phage imaging, how it affected our knowledge on these viruses and recent developments in the field. peerReviewed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-11-01 |