6533b836fe1ef96bd12a1364
RESEARCH PRODUCT
Fluoro heterocycles. A photochemical methodology for the synthesis of 3-amino- and 3-(N-alkylamino)-5-perfluoroalkyl-1,2,4-oxadiazoles
Nicolò VivonaAndrea PaceSilvestre Buscemisubject
chemistry.chemical_compoundAmmoniaPrimary (chemistry)ChemistryOrganic ChemistryDrug DiscoveryPhotodissociationMethanolIrradiationPhotochemistryBiochemistrydescription
Abstract A photochemical methodology for the synthesis of perfluoroalkyl-1,2,4-oxadiazoles has been described. 3-Amino- and 3-( N -alkylamino)-5-perfluoroalkyl-1,2,4-oxadiazoles have been prepared by irradiation of 3-perfluoroalkanoylamino-4-phenyl-1,2,5-oxadiazoles (furazans) at λ =313 nm in methanol and in the presence of ammonia or primary aliphatic amines.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-10-01 | Tetrahedron Letters |