6533b836fe1ef96bd12a1c14

RESEARCH PRODUCT

Zur Reaktion von Indolen mit 1,3-Dithiolenium-Ionen: ein einfacher Zugang zu 3-(1,3-Dithiolan-2-yl)indolen

Eyup AkgünUlf PindurMustafa Tunali

subject

Indole testBicyclic moleculeChemistryOrganic ChemistryRegioselectivityOrganic chemistryNuclear magnetic resonance spectroscopyPhysical and Theoretical ChemistryMedicinal chemistry

description

Reaction of Indoles with 1,3-Dithiolenium Ions: a Simple Access to 3-(1,3-Dithiolan-2-yl)indoles 3-Unsubstituted indoles 1 react regioselectively with 2-methyl- and 2-phenyl-1,3-dithiolenium ions 2 under mild conditions to give the 3-(1,3-dithiolan-2-yl)indoles 4 as protected 3-acylindoles.

https://doi.org/10.1002/jlac.198619860912