Design of novel small molecule base-pair recognizers of toxic CUG RNA transcripts characteristics of DM1.

6533b837fe1ef96bd12a1dde

RESEARCH PRODUCT

Design of novel small molecule base-pair recognizers of toxic CUG RNA transcripts characteristics of DM1.

Alex Perálvarez-marín ÁNgel Lirio Roger Estrada-tejedor Germana Falcone Beatrice Cardinali Claudia Provenzano Manuel Pérez-alonso Raül Ondoño Carlos Elvira Elena ÁLvarez-marimon José I. Borrell

subject

Untranslated region congenital hereditary and neonatal diseases and abnormalities Base pair Myotonic dystrophy Biophysics Computational biology Base recognition Biology Biochemistry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Structural Biology RNA targeting Genetics MBNL1 030304 developmental biology ComputingMethodologies_COMPUTERGRAPHICS 0303 health sciences Drug discovery Alternative splicing RNA Biological activity Non-coding RNA Computer Science Applications chemistry 030220 oncology & carcinogenesis Molecular modelling TP248.13-248.65 Small molecule Biotechnology Research Article

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year	journal	country	edition	language
2020-09-20	Computational and structural biotechnology journal

10.1016/j.csbj.2020.11.053 https://pubmed.ncbi.nlm.nih.gov/33363709

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