6533b837fe1ef96bd12a1e1f

RESEARCH PRODUCT

Polymer-based materials modified with magnetite nanoparticles for enrichment of phospholipids

S. Meseguer-lloretErnesto F. Simó-alfonsoIsabel Ten-doménechJosé Manuel Herrero-martínezHéctor Martínez-pérez-cejuelaS. Torres-cartas

subject

SorbentScanning electron microscope010402 general chemistry01 natural sciencesAnalytical ChemistryLimit of DetectionQUIMICA ANALITICAHumansSolid phase extractionChromatography-evaporative light scattering detectionMagnetite NanoparticlesChromatography High Pressure LiquidPhospholipidschemistry.chemical_classificationSolid-phase extractionChromatographyHydrophilic interaction liquidMilk HumanHydrophilic interaction chromatography010401 analytical chemistryExtraction (chemistry)Solid Phase ExtractionHuman milkPolymer0104 chemical sciencesSolventchemistryMagnetic nanoparticlesEpoxy CompoundsMethacrylatesMagnetic polymer-based materialHydrophobic and Hydrophilic Interactions

description

[EN] A polymeric material modified with magnetic nanoparticles (MNPs) has been synthesized and evaluated as sorbent both for solid-phase extraction (SPE) and dispersive magnetic solid-phase extraction (MSPE) of phospholipids (PLs) in human milk samples. The synthesized sorbent was characterized by scanning electron microscopy and its iron content was also determined. Several experimental variables that affect the extraction performance (e.g. loading solvent, breakthrough volume and loading capacity) were investigated and a comparison between conventional SPE and MSPE modalities was done. The proposed method was satisfactorily applied to the analysis of PLs in human milk fat extracts in different lactation stages and the extracted PLs were determined by means of hydrophilic interaction liquid chromatography using evaporative light scattering detection.

yearjournalcountryeditionlanguage
2018-01-01
10.1016/j.talanta.2017.12.042https://hdl.handle.net/10251/141525