6533b837fe1ef96bd12a2011
RESEARCH PRODUCT
COMPARISON OF T-1 ESTIMATION TECHNIQUES IN CARDIAC MRI
Paul WalkerPierre-yves MarieAlain BertrandNicolas Danchinsubject
AdultMaleBiomedical EngineeringBiophysicsInversion recovery030204 cardiovascular system & hematologyTISSUE CHARACTERIZATION030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineNuclear magnetic resonanceCARDIAC MRIQUALITY CONTROL[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansRadiology Nuclear Medicine and imagingMathematicsReproducibility[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingHealthy subjectsHeartTissue characterizationT-1Magnetic Resonance ImagingFemalePreclinical imagingdescription
International audience; Abstract: We have shown that the use of a simple combination of inversion recovery/spin-echo (IR/SE) sequences provides undeniably superior precision in quantitative in vivo myocardium T-1 estimation than the standard multiple spin-echo approach. On a group of 25 healthy subjects, the T-1 dispersion was, respectively, 3.8% for the IR/SE combination and 19.6% for the best SE pair combination. Moreover, repeated measurements were carried out on seven of the volunteers in order to assess T-1 reproducibility. The mean intra-individual T-1 precision was found to be 2.8% for the IR/SE pair and 20.0% for the best SE pair. The in vivo imaging work was supported and corroborated by a thorough treatment of the theoretical T-1 errors. We also highlight the importance of quality control in quantitative MRI; a correction being required in the SE sequences to bring measured signal intensities into line with those predicted from simple theory.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-01-01 |