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RESEARCH PRODUCT

Synthesis, characterisation and complexation of di- and trifunctional hybrid ferrocenylphosphine ligands.

subject

description

Organometallic compounds with at least one metal-carbon bond are used in various fields of chemistry: for example, in medical research for anticancer treatments, in catalytic reactions as catalysts or ligands, in electrochemistry for their redox potentials, in materials chemistry for their optical and electronic properties. The principal family of organometallic compounds of this thesis is ferrocene due to its physical and chemical properties particularly its robustness and the possibility of multiple substitutions on cyclopentadienyl ligands, the dissymmetric functionalization of these cyclopentadienyl rings being a major challenge.The first part of this thesis describes the bibliography of syntheses of phosphorus-containing hybrid ferrocene compounds and their studies as ligands in coordination chemistry and catalysis.The second part focuses on the development of two new hybrid ferrocene families [Brönsted acid/Lewis base] on a dialkylated ferrocene platform with constrained conformation. More precisely, the synthesis and complexation of ligands type [PR2/CO2H] and [PR2/CONHCH2SO3NHEt3] have been done. Interestingly, the evolution of the former ligand type by amidation allows us to have an access to more polar ferrocene families (latter type).The third part investigates the development of trifunctional hybrid ferrocenes type [phosphine/aminoacid]. Various aminoacids have been introduced to diversify steric environments, lock the ligand structures and favor various modes of complexation with transition metals to use in selective catalysis.