6533b837fe1ef96bd12a28f4
RESEARCH PRODUCT
Cloning and sequencing of the cDNA encoding human glutaredoxin.
Hiroki NanriKoichiro TakeshigeYasuyuki FukumakiM. Rohan FernandoSadaaki IwanagaShigeki MinakamiShun Ichiro KawabataHideki Sumimotosubject
DNA ComplementaryMolecular Sequence DataBiophysicsSequence alignmentMolecular cloningBiologyBiochemistryStructural BiologyGlutaredoxinComplementary DNAGeneticsHumansAmino Acid SequenceCloning MolecularPeptide sequenceGlutaredoxinschemistry.chemical_classificationBase SequencecDNA libraryNucleic acid sequenceBrainProteinsMolecular biologyAmino acidchemistryBiochemistryOxidoreductasesdescription
Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-06-01 | Biochimica et biophysica acta |