6533b837fe1ef96bd12a2c7c

RESEARCH PRODUCT

Effects of apomorphine on orienting reaction in the rat

Maurizio CasarrubeaFilippina SorberaGiuseppe Crescimanno

subject

Head turningDopamineA9 and A10 neuronsensorimotor integrationapomorphine

description

Aim of the research was to study the possible relationship between rapid apomorphine-induced modifications of midbrain dopaminergic neuron activity and rapid modifications of a motor response triggered by sensory stimuli (sensory-motor integration. Following apomorphine administration, ANOVA test revealed significant decrease of head turning latency and duration. A change on dopamine release, leading to an inhibition or facilitation of dopamine-mediated responses to environmental stimuli, may be hypothesized.

http://hdl.handle.net/10447/50585