6533b837fe1ef96bd12a3053

RESEARCH PRODUCT

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subject

0301 basic medicineMultidisciplinarybiologyChemistryPhosphataseProtein tyrosine phosphataseImmunoglobulin ECell biologyTranscriptome03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureAntigenGene expressionbiology.proteinmedicineBone marrow030217 neurology & neurosurgeryGlucocorticoidmedicine.drug

description

Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type and PEST-domain-enriched tyrosine phosphatase (PEP) null mice, activated by immunoglobulin E sensitization and dinitrophenol treatment, and additionally treated with the glucocorticoid dexamethasone. The transcriptomics experiment was performed in duplicate with a total of 16 samples (GSE108972).