6533b837fe1ef96bd12a305a
RESEARCH PRODUCT
Preparation of Indoles from α-Aminonitriles: A Short Synthesis of FGIN-1-27
Till OpatzDorota Ferencsubject
Simple (abstract algebra)ChemistryYield (chemistry)fungiOrganic ChemistryPhysical and Theoretical ChemistryBiochemistryCombinatorial chemistrydescription
α-Aminonitriles derived from 2-aminocinnamic acid esters and amides can be cyclized under basic conditions to furnish substituted indole-3-acetic acid derivatives in quantitative yield. The reaction provides a simple access to a class of biologically active compounds.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-09-01 | Organic Letters |