6533b837fe1ef96bd12a3083
RESEARCH PRODUCT
ChemInform Abstract: Oxidative Transformation of Aryls Using Molybdenum Pentachloride
Siegfried R. WaldvogelSimon Trosiensubject
Reaction rateAqueous solutionchemistryMolybdenumReagentchemistry.chemical_elementOxidative coupling of methaneGeneral MedicineOxidative phosphorylationLewis acids and basesMolybdenum pentachlorideCombinatorial chemistrydescription
Molybdenum pentachloride combines a strong Lewis acid character with an unusually high oxidation potential creating a powerful reagent for oxidative transformations. Since the oxidative coupling reaction of aryls is induced at an extraordinarily high reaction rate, a variety of labile groups, e.g. iodo, tert-alkyl, etc., are tolerated on the aromatic core. Furthermore, the co-formed molybdenum salts can either be exploited for template effects to obtain uncommon geometries in a preferred manner, or redox-play starts after aqueous workup. Therefore MoCl5 represents a unique and easily available reagent.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-12-10 | ChemInform |