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RESEARCH PRODUCT

Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety

Andrés Coca-pelazAlfio FerlitoManuel Bernal-sprekelsenJuan P. RodrigoPrimoz StrojanPetra AmbroschKatherine A. HutchesonVincent Vander PoortenFabian García-velascoBenedikt J. FolzAlessandra RinaldoCarlos SuárezCarl E. Silver

subject

MaleGlottisMicrosurgerymedicine.medical_specialtycomplicationsLaryngectomyTreatment resultselderly03 medical and health sciencesPostoperative Complications0302 clinical medicineOverall survivalHumansMedicineEffective treatmentTransoral laser microsurgerycomplications; elderly; laryngeal cancer; transoral laser microsurgery; Otorhinolaryngology2734 Pathology and Forensic Medicine030223 otorhinolaryngologytransoral laser microsurgeryLaryngeal NeoplasmsAgedRetrospective Studiesbusiness.industryOtorhinolaryngology2734 Pathology and Forensic MedicineBackground dataAge FactorsRetrospective cohort studySurgeryTreatment OutcomeOtorhinolaryngologyGlottic cancer030220 oncology & carcinogenesisCarcinoma Squamous Celllaryngeal cancerFemaleLaser Therapybusiness

description

Background Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited. Methods A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed. Results Six patients (8%) had postoperative complications, but no treatment-related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five-year disease-specific survival (DSS), overall survival, and laryngectomy-free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates. Conclusions Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.

yearjournalcountryeditionlanguage
2018-06-25Head & Neck
https://doi.org/10.1002/hed.25616