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RESEARCH PRODUCT
Electrochemical Synthesis of 2-Hydroxy-para-terphenyls by Dehydrogenative Anodic C–C Cross-Coupling Reaction
Robert FrankeSiegfried R. WaldvogelSebastian Lipssubject
C c coupling010405 organic chemistryChemistryOrganic Chemistry010402 general chemistryElectrochemistry01 natural sciencesCombinatorial chemistryCoupling reaction0104 chemical sciencesAnodedescription
The anodic C–C cross-coupling reaction provides fast access to a wide range of bi- and terarylic scaffolds by electrochemically mediated arylation reactions. Herein, a metal- and reagent-free electrosynthetic protocol for the synthesis of nonsymmetrical 2-hydroxy-para-teraryl derivatives is presented for the first time. It is scalable, easy to conduct, and allows the use of a broad variety of different functional groups.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-08 | Synlett |