4-[5-(4-Fluorophenyl)-3-isopropylisoxazol-4-yl]pyridine

6533b838fe1ef96bd12a45db

RESEARCH PRODUCT

4-[5-(4-Fluorophenyl)-3-isopropylisoxazol-4-yl]pyridine

Christian Peifer Stefan Laufer Dieter Schollmeyer Mohammed Abadleh

subject

chemistry.chemical_compound Molecular geometry MAPK Inhibitors chemistry Stereochemistry Pyridine General Materials Science Biological activity General Chemistry Isoxazole Condensed Matter Physics Ring (chemistry)Isopropyl

description

In the title compound, C17H15FN2O, the exocyclic bond angles at the C atoms of the isoxazole ring bearing the pyridyl and 4-fluorophenyl substituents are 129.66 (17) and 134.58 (16)°, respectively. The structure was determined in a study of the molecular geometry of isoxazole derivatives with biological activity as MAPK inhibitors.

year	journal	country	edition	language
2006-08-02	Acta Crystallographica Section E Structure Reports Online

https://doi.org/10.1107/s1600536806029448

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