6533b839fe1ef96bd12a5c88
RESEARCH PRODUCT
One-Component DNA Mechanoprobes for Facile Mechanosensing in Photopolymerized Hydrogels and Elastomers.
Guido CreusenAndreas WaltherRicarda Sophia Schmidtsubject
Materials sciencePolymers and Plastics010405 organic chemistryPolymersOrganic ChemistryHydrogelsDNA010402 general chemistryElastomer01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistryChemical engineeringElastomersComponent (UML)Self-healing hydrogelsPrinting Three-DimensionalMaterials ChemistryDNAdescription
DNA mechanosensors offer unique properties for mechano-adaptive and self-reporting materials, such as programmable bond strength and geometrical strain response, tunable fluorescent strain sensing, interfacing to biological systems, and the ability to store mechanical information. However, the facile incorporation of advanced DNA motifs into polymer networks and achieving robustness in application settings remain difficult. Herein, we introduce one-component DNA mechanoprobes that can be easily polymerized into polymer hydrogels and even elastomers to allow strain-induced fluorescence sensing. The all-in-one mechanoprobe contains a DNA hairpin for programmable force sensing, an internal fluorophore-quencher pair as a reporter, and methacrylamide groups on both ends for rapid and facile photopolymerization into networks based on the nontoxic water-soluble monomer methoxy triethylene glycol acrylate (mTEGA). In addition to mechanosensing hydrogels, we utilize the low
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-05-13 | ACS macro letters |