6533b839fe1ef96bd12a66b8

RESEARCH PRODUCT

CTX-M β-Lactamase-Producing Escherichia coli in French Hospitals: Prevalence, Molecular Epidemiology, and Risk Factors▿

Albert SottoJulien DelmasLaurent CavaliéEvelyne LecaillonJérôme MoreauHélène Jean-pierreN. BouzigesRichard BonnetHélène MarchandinJean-philippe Lavigne

subject

MaleMESH : Escherichia coliMESH : PrevalenceEpidemiologyMESH : AgedMESH: beta-LactamasesMESH: Urinary Tract Infectionsmedicine.disease_causeMESH: Risk Factors[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesRisk FactorsGenotypePrevalenceMESH : Urinary Tract InfectionsMESH : FemaleMESH: PhylogenyEscherichia coli InfectionsPhylogenyGel electrophoresisMESH: Aged0303 health sciencesMolecular EpidemiologybiologyMESH: Escherichia coliMESH : beta-LactamasesMESH: HospitalsEnterobacteriaceaeMESH : Risk FactorsHospitals3. Good healthElectrophoresis Gel Pulsed-FieldMESH : Hospitals[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesMESH: Electrophoresis Gel Pulsed-FieldMESH : Escherichia coli InfectionsUrinary Tract Infections[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesFemaleFranceMicrobiology (medical)Urinary systemMESH : Malebeta-LactamasesMicrobiologyMESH : Epidemiology Molecular03 medical and health sciencesMESH: Epidemiology MolecularmedicineEscherichia coliHumansRisk factorMESH : FranceEscherichia coliMESH: Prevalence030304 developmental biologyMESH : Electrophoresis Gel Pulsed-FieldMESH: Escherichia coli InfectionsAgedMESH: HumansMolecular epidemiology030306 microbiologyMESH : HumansMESH : Phylogenybiology.organism_classificationMESH: MaleMESH: FranceMESH: FemaleBacteria

description

ABSTRACT In 2004, 65 CTX-M-producing Escherichia coli isolates were collected from infected patients in four French hospitals. The bla CTX-M-15 genes were predominant. Pulsed-field gel electrophoresis highlighted a clonal propagation of CTX-M-15-producing strains belonging to phylogenetic group B2, notably in the community. The main risk factors for acquiring these isolates were urinary tract infections or the presence of a urinary catheter in diabetic or renal failure patients.

10.1128/jcm.01917-06https://europepmc.org/articles/PMC1829058/