6533b839fe1ef96bd12a6ec8

RESEARCH PRODUCT

Phylogeny of viroids, viroidlike satellite RNAs, and the viroidlike domain of hepatitis delta virus RNA.

Ricardo FloresTheodor O. DienerJoaquín DopazoSantiago F. ElenaAndrés Moya

subject

GeneticsMultidisciplinaryPhylogenetic treeRNABiologyVirusoidVirologyModels BiologicalVirusViroidsDomain (software engineering)MonophylyPhylogeneticsRNARNA SatelliteRNA ViralHepatitis Delta VirusLiving fossilPhylogenyResearch Article

description

We report a phylogenetic study of viroids, some plant satellite RNAs, and the viroidlike domain of human hepatitis delta virus RNA. Our results support a monophyletic origin of these RNAs and are consistent with the hypothesis that they may be "living fossils" of a precellular RNA world. Moreover, the viroidlike domain of human hepatitis delta virus RNA appears closely related to the viroidlike satellite RNAs of plants, with which it shares some structural and functional properties. On the basis of our phylogenetic analysis, we propose a taxonomic classification of these RNAs.

yearjournalcountryeditionlanguage
1991-07-01
https://europepmc.org/articles/PMC51931/