6533b83afe1ef96bd12a70ec
RESEARCH PRODUCT
Thymidine-, uridine- and choline-kinase in rabbit kidney cells infected with herpesvirus hominis, type I and II.
S. DundaroffDietrich Falkesubject
SerotypeCholine kinaseBiologyKidneyThymidine KinaseCholinechemistry.chemical_compoundSpecies SpecificityVirologyCulture TechniquesRabbit kidneyAnimalsSimplexvirusSerotypingUridineCells Culturedchemistry.chemical_classificationStrain (chemistry)PhosphotransferasesGeneral MedicineVirologyUridineEnzymechemistryGiant cellRabbitsThymidinedescription
Data are presented about the activity of the thymidine-, uridine- and choline-kinase after infection with 21 strains ofherpesvirus hominis of serotype I or II in rabbit kidney cells. Type I strains increase the activity of the thymidine-kinase 15–20 fold over the controls, whereas the type II strains demonstrate a moderate activity, the level of the enzyme is increased 2–5 fold. One giant cell forming strain exhibits unusual properties, the TK activity decreases in correlation to the controls. The uridine- and choline-kinases induce the respective enzymes in different manner. The strains tested are divided into 5 groups depending upon the activity of the enzymatic activity. The implications of the results are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1972-03-01 | Archiv fur die gesamte Virusforschung |