6533b83afe1ef96bd12a7154
RESEARCH PRODUCT
Saponin with antibacterial activity from the roots of Albizia adianthifolia
Gaiëlle SonfackCedric Fossi TchindaIngrid Konga SimoGabin Thierry M. BitchagnoBlaise Kemajou NganouİLhami ÇElikMathieu TeneSultan Funda GörkemTill OpatzVeronique Penlap BengVictor KuetePierre Tanesubject
description
An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128 μg/mL.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 |