6533b83afe1ef96bd12a715b

RESEARCH PRODUCT

The excellent biocompatibility and negligible immune response of the titanium heterometallic MOF MUV-10

B. SastreVictoria Del PozoCarlos Marti-gastaldoIsabel Abánades LázaroMaría Romero ÁNgelJosé M Rodrigo-muñoz

subject

BiocompatibilityBiomedical Engineeringchemistry.chemical_elementBiocompatible Materials02 engineering and technology010402 general chemistry01 natural sciencesMiceImmune systemMaterials TestingAnimalsHumansGeneral Materials ScienceParticle SizeCytotoxicityMetal-Organic FrameworksTitaniumfungiPhosphate buffered salineImmunityGeneral ChemistryGeneral Medicine021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical scienceschemistryDegradation (geology)Calcium0210 nano-technologyTitanium

description

The Ti-Ca heterometallic MOF MUV-10 exhibits good dispersibility in phosphate buffer and low phosphate-induced degradation in comparison to other MOF systems. It induces no cytotoxicity towards cells of the immune system and no inmune response, making it an attractive candidate for biomedical applications and demonstrating its safe use for other applications.

10.1039/d1tb00981hhttp://dx.doi.org/10.1039/d1tb00981h