Risperidona lietošana bērniem ar autismu vai šizofrēniju un ar to saistīto risku izvērtējums

6533b83afe1ef96bd12a73f4

RESEARCH PRODUCT

Risperidona lietošana bērniem ar autismu vai šizofrēniju un ar to saistīto risku izvērtējums

Jekaterina Livšina

subject

Farmācija bērni ar šizofrēniju hiperprolaktinēmija terapijas maiņa risperidons bērni ar autismu

description

Risperidons ir efektīvs un plaši pielietots neiroleptiskais līdzeklis, kura lietošana bērniem ar autismu vai šizofrēniju bieži saistīta ar hiperprolaktinēmijas attīstīšanos. Pētījumā apkopoti dati par risperidona nozīmēšanas biežumu Bērnu Psihiatrijas Klīnikā, hiperpolaktinēmijas attīstības risku un to atkarību no bērna dzimuma. Darbā secināts, ka autisma un šizofrēnijas pacientiem pastāv ļoti augsts hiperprolaktinēmijas risks -61% autisma un 94% šizofrēnijas pacientiem noteikta risperidona izraisīta hiperprolaktinēmija. Pētījumā izvērtēta bērnu vecāku informētība par risperidona lietošanas riskiem. Pie hipeprolaktinēmijas autisma gadījumā pacientiem medicīniskās palīdzības pamatmetode ir risperidona atcelšana un pedagoģiska korekcija. Pacientiem ar šizofrēniju, terapija ar risperidonu tiek mainīta uz citiem jaunās paaudzes neiroleptiķiem.

year	journal	country	edition	language
2015-01-01

https://dspace.lu.lv/dspace/handle/7/30864

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