6533b83afe1ef96bd12a7851
RESEARCH PRODUCT
ChemInform Abstract: Pyrrolo[3,4-e][1,2,3]triazolo[1,5-a]pyrimidine and Pyrrolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine. New Tricyclic Ring Systems of Biological Interest.
Gaetano DattoloGirolamo CirrincioneAnna Maria AlmericoPatrizia DianaAntonino LauriaPaola Barrajasubject
chemistry.chemical_classificationchemistry.chemical_compoundAcetonitrileschemistryPyrimidineStereochemistryDimethyl sulfoxideTriazole derivativesGeneral MedicineRing (chemistry)D-1Tricyclicdescription
Derivatives of the new ring system pyrrolo[3,4-e][1,2,3] triazolo[1,5-a]pyrimidine 6 were prepared in high yields in one step by reaction of 3-azidopyrrole 3 and substituted acetonitriles. Compound 6b rearranged, upon heating in dimethyl sulfoxide in the presence of water, to pyrrolo[3,4-d][1,2,3]triazolo-[1,5-a]pyrimidine 7.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-01-09 | ChemInform |