6533b83afe1ef96bd12a7877

RESEARCH PRODUCT

Reductive Metabolism of P-Nitrobenzoic Acid and Nitrazepam in the Isolated Perfused Rat Liver in the Presence of Ethanol

H. G. Jonen

subject

chemistry.chemical_compoundReductive metabolismEthanolNitrazepamBiochemistryChemistryRat livermedicineNitroP-nitrobenzoic acidmedicine.drug

description

Reductive metabolism of aromatic nitro compounds has been shown to play a minor role under aerobic conditions and to reach maximal activities under anoxia (Jonen-Kern et al., Xenobiotica, in press). We have shown that in the presence of ethanol maximal activities can be obtained even under aerobic conditions.

https://doi.org/10.1007/978-3-662-39532-5_41